FORMULATION AND EVALUATION OF STABILITY OF THAI PURPLE RICE BRAN-BASED COSMETIC PRODUCTS

Authors

  • Chaiyavat Chaiyasut Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
  • Periyanaina Kesika Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
  • Poomchon Sakdakampanat Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
  • Sartjin Peerajan Health Innovation Institute, Chiang Mai 50230, Thailand.
  • Bhagavathi Sundaram Sivamaruthi Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand. http://orcid.org/0000-0002-5499-8350

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i1.22073

Keywords:

Antioxidants, Cosmetic, Thai purple rice, Rice bran, Rice bran oil, Heavy metals

Abstract

Objective: The rice bran (RB) phytochemicals are known for several pharmacological properties.  The current study aimed to extract the active principles from Thai purple rice bran, formulate the cosmetic products, evaluate the physical property, and stability of the products.

Methods: The RB was prepared by 80% ethanolic extraction, and measured the total phenolic and anthocyanin content by HPLC, and spectrophotometric methods. The antioxidant capacity of RB oil (RBO), RB extract (RBE) was assessed by spectrophotometric methods. The cosmetic products were formulated with rice bran extract and fermented and distilled purple rice solution (FDPRS). The stability of the formulations was assessed. The heavy metal and microbial contamination were determined by atomic absorption spectrometry, and plating assay, respectively.

Results: The yield of PRE and RBO was 0.92, and 1.62%, respectively. The total phenolic and anthocyanin content of PRE was 305.30 ± 6.15 mg gallic acid/g of extract, and 877.33 ± 87.73 mg cyanidin chloride /g of extract, respectively. RBO, PRE, and FDPRS exhibited high antioxidant capacity. The cosmetic formulations were physically stable in the heat-cool cycle, and the stability of active compounds was not affected while stored at 30°C for two months. The storage temperature affected the phenolic compounds present in the cosmetic formulations, especially at 45°C. There was no significant decrease in oryzanol content of soap formulation. All the formulations were free microbial and heavy metal contamination.

Conclusion: The rice bran phytochemical based cosmetic products are rich in antioxidants, stable, free from heavy metals and microbial contaminations, and further fine tuning of the formulation may achieve the market quality.

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Published

01-01-2018

How to Cite

Chaiyasut, C., P. Kesika, P. Sakdakampanat, S. Peerajan, and B. S. Sivamaruthi. “FORMULATION AND EVALUATION OF STABILITY OF THAI PURPLE RICE BRAN-BASED COSMETIC PRODUCTS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 1, Jan. 2018, pp. 99-104, doi:10.22159/ajpcr.2018.v11i1.22073.

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