FORMULATION AND EVALUATION OF STABILITY OF THAI PURPLE RICE BRAN-BASED COSMETIC PRODUCTS


Chaiyavat Chaiyasut, Periyanaina Kesika, Poomchon Sakdakampanat, Sartjin Peerajan, Bhagavathi Sundaram Sivamaruthi

Abstract


Objective: The rice bran (RB) phytochemicals are known for several pharmacological properties.  The current study aimed to extract the active principles from Thai purple rice bran, formulate the cosmetic products, evaluate the physical property, and stability of the products.

Methods: The RB was prepared by 80% ethanolic extraction, and measured the total phenolic and anthocyanin content by HPLC, and spectrophotometric methods. The antioxidant capacity of RB oil (RBO), RB extract (RBE) was assessed by spectrophotometric methods. The cosmetic products were formulated with rice bran extract and fermented and distilled purple rice solution (FDPRS). The stability of the formulations was assessed. The heavy metal and microbial contamination were determined by atomic absorption spectrometry, and plating assay, respectively.

Results: The yield of PRE and RBO was 0.92, and 1.62%, respectively. The total phenolic and anthocyanin content of PRE was 305.30 ± 6.15 mg gallic acid/g of extract, and 877.33 ± 87.73 mg cyanidin chloride /g of extract, respectively. RBO, PRE, and FDPRS exhibited high antioxidant capacity. The cosmetic formulations were physically stable in the heat-cool cycle, and the stability of active compounds was not affected while stored at 30°C for two months. The storage temperature affected the phenolic compounds present in the cosmetic formulations, especially at 45°C. There was no significant decrease in oryzanol content of soap formulation. All the formulations were free microbial and heavy metal contamination.

Conclusion: The rice bran phytochemical based cosmetic products are rich in antioxidants, stable, free from heavy metals and microbial contaminations, and further fine tuning of the formulation may achieve the market quality.


Keywords


Antioxidants, Cosmetic, Thai purple rice, Rice bran, Rice bran oil, Heavy metals.

| PDF |

References


Milam EC, Rieder EA. An approach to cosmeceuticals. J Drugs Dermatol 2016;15:452-6.

Pengkumsri N, Chaiyasut C, Saenjum C, Sirilun S, Peerajan S, Suwannalert P, et al. Physicochemical and anti-oxidative properties of black, brown and red rice varieties of northern Thailand. Food Sci Technol (Campinas)2015;35:331-8.

Pengkumsri N, Sivamaruthi BS, Sirilun S, Suwannalert P, Rodboon T, Prasitpuriprecha C, et al. Dietary supplementation of Thai black rice bran extract and yeast beta-glucan protects the dextran sodium sulphate mediated colitis induced rat. RSC Adv 2017;7:396-402.

Marko D, Puppel N, Tjaden Z, Jakobs S, Pahlke G. The substitution pattern of anthocyanidins affects different cellular signaling cascades regulating cell proliferation. Mol Nutr Food Res 2004;48:318-25.

Chaiyasut C, Sivamaruthi BS, Pengkumsri N, Keapai W, Kesika P, Saelee M, et al. Germinated thai black rice extract protects experimental diabetic rats from oxidative stress and other diabetes-related consequences. Pharmaceuticals (Basel)2016;10. pii: E3.

Canter PH, Ernst E. Anthocyanosides of Vaccinium myrtillus (bilberry) for night vision-a systematic review of placebo-controlled trials. Surv Ophthalmol 2004;49:38-50.

Lau FC, Shukitt-Hale B, Joseph JA. Nutritional intervention in brain aging: Reducing the effects of inflammation and oxidative stress. In: Harris RE, editor. Inflammation in the Pathogenesis of Chronic Diseases. New York: Springer; 2007. p. 299-318.

Settharaksa S, Madaka F, Charkree K, Charoenchai L. The study of anti-inflammatory and antioxidant activity in cold press rice bran oil from rice in Thailand. Int J Pharm Pharm Sci 2014;6:428-31.

Choi JS, Jeon MH, Moon WS, Moon JN, Cheon EJ, Kim JW, et al. In vivo hair growth-promoting effect of rice bran extract prepared by supercritical carbon dioxide fluid. Biol Pharm Bull 2014;37:44-53.

Choi JS, Park JB, Moon WS, Moon JN, Son SW, Kim MR. Safety and efficacy of rice bran supercritical CO2 extract for hair growth in androgenic alopecia: A 16-week double-blind randomized controlled trial. Biol Pharm Bull 2015;38:1856-63.

Miyazawa M, Oshima T, Koshio K, Itsuzaki Y, Anzai J. Tyrosinase inhibitor from black rice bran. J Agric Food Chem 2003;51:6953-6.

Choi SP, Kim SP, Kang MY, Nam SH, Friedman M. Protective effects of black rice bran against chemically-induced inflammation of mouse skin. J Agric Food Chem 2010;58:10007-15.

Bernardi DS, Pereira TA, Maciel NR, Bortoloto J, Viera GS, Oliveira GC, et al. Formation and stability of oil-in-water nanoemulsions containing rice bran oil: In vitro and in vivo assessments. J Nanobiotechnology 2011;9:44.

Manosroi A, Chutoprapat R, Abe M, Manosroi W, Manosroi J. Anti-aging effect of topical formulations containing niosomes entrapped with rice bran bioactive compounds. Pharm Biol 2012;50:208-24.

Hanno I, Centini M, Anselmi C, Bibiani C. Green cosmetic surfactant from rice: Characterization and application. Cosmetics 2015;2:322-41.

Vichit W, Saewan N. Antioxidant activities and cytotoxicity of Thai pigmented rice. Int J Pharm Pharm Sci 2015;7:329-34.

Daud NS, Zaidel DN, Song LK, Muhamad II, Jusoh YM. Antioxidant properties of rice bran oil from different varieties extracted by solvent extraction methods. J Teknol (Sci Engn) 2016;78:107-10.

Sukrasno S, Tuty S, Fidrianny I. Antioxidant evaluation and phytochemical content of various rice bran extracts of three varieties rice from Semarang central Java, Indonesia. Asian J Pharm Clin Res 2017;10:377-82.

Pengkumsri N, Chaiyasut C, Sivamaruthi BS, Saenjum C, Sirilun S, Peerajan S, et al. The influence of extraction methods on composition and antioxidant properties of rice bran oil. Food Sci Technol (Campinas)2015;35:493-501.

Matouk AM, El-Kholy MM, El-Sadany M, Hendawy YT. Rice bran oil extraction using an expeller machine. Misr J Agric Eng 2009;26:324-42.

Chaiyasut C, Pengkumsri N, Sirilun S, Peerajan S, Khongtan S, Sivamaruthi BS. Assessment of changes in the content of anthocyanins, phenolic acids, and antioxidant property of Saccharomyces cerevisiae mediated fermented black rice bran. AMB Express 2017;7:114.

Chaiyasut C, Sivamaruthi BS, Peerajan S, Sirilun S, Chaiyasut K, Kesika P. Assessment of heavy metals, minerals, alcohol, and fusel oil content of selected fermented plant beverages of Thailand. Int Food Res J 2017;24:126-33.

Horwitz W. Official Methods of Analysis of AOAC International. Vol. 1. Gaithersburg, MD: AOAC International; 2000.

Pattananandecha T, Sirilun S, Duangjitcharoen Y, Sivamaruthi BS, Suwannalert P, Peerajan S, et al. Hydrolyzed inulin alleviates the azoxymethane-induced preneoplastic aberrant crypt foci by altering selected intestinal microbiota in Sprague-Dawley rats. Pharm Biol 2016;54:1596-605.

Chaiyasut C, Pattananandecha T, Sirilun S, Suwannalert P, Peerajan S, Sivamaruthi BS. Synbiotic preparation with lactic acid bacteria and inulin as a functional food: In vivo evaluation of microbial activities, and preneoplastic aberrant crypt foci. Food Sci Technol (Campinas)2017;37:328-36.

Sirilun S, Sivamaruthi BS, Kumar N, Kesika P, Peerajan S, Chaiyasut C. Lactobacillus-fermented plant juice as a potential ingredient in cosmetics: Formulation and assessment of natural mouthwash. Asian J Pharm Clin Res 2016;9 Suppl 3:52-6.

Sirilun S, Chaiyasut C, Sivamaruthi BS, Peerajan S, Kumar N, Kesika P. Phenethyl alcohol is an effective non-traditional preservative agent for cosmetic preparations. Asian J Pharm Clin Res 2017;10:129-33.

Kanlayavattanakul M, Lourith N, Chaikul P. Jasmine rice panicle: A safe and efficient natural ingredient for skin aging treatments. J Ethnopharmacol 2016;193:607-16.




About this article

Title

FORMULATION AND EVALUATION OF STABILITY OF THAI PURPLE RICE BRAN-BASED COSMETIC PRODUCTS

Topics

Rice phytochemicals

Keywords

Antioxidants, Cosmetic, Thai purple rice, Rice bran, Rice bran oil, Heavy metals.

DOI

10.22159/ajpcr.2018.v11i1.22073

Date

01-01-2018

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 11 Issue 1 January 2018 Page: 99-104

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

57 Views | 161 Downloads

Authors & Affiliations

Chaiyavat Chaiyasut
Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

Periyanaina Kesika
Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

Poomchon Sakdakampanat
Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.

Sartjin Peerajan
Health Innovation Institute, Chiang Mai 50230, Thailand.

Bhagavathi Sundaram Sivamaruthi
Innovation Center for Holistic Health, Nutraceuticals, and Cosmeceuticals, Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200, Thailand.
Thailand


Article Tools


Email this article (Login required)
Email the author (Login required)

Refbacks

  • There are currently no refbacks.