DIFFERENCES OF SALIVA LEPTIN LEVELS IN CHILDREN WITH CHRONIC KIDNEY DISEASE ON HEMODIALYSIS AND HEALTHY CHILDREN (STUDY IN CHILDREN WITH GINGIVITIS)

BERTHAULI ESTER NURMAIDA; Heriandi Sutadi; Sarworini B Budiardjo; Eka Laksmi Hidayati

doi:10.22159/ajpcr.2018.v11i4.23276

Authors

BERTHAULI ESTER NURMAIDA Department of Pediatric, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.
Heriandi Sutadi Department of Pediatric, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.
Sarworini B Budiardjo Department of Pediatric, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.
Eka Laksmi Hidayati Department of Pediatric Nephrology,Dr. Cipto Mangunkusumo Hospital, Universitas Indonesia, Jakarta 10430, Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i4.23276

Keywords:

Chronic kidney disease, Hemodialysis, Gingivitis, Salivary leptin

Abstract

Â Objectives: Analyze the difference of salivary leptin in between healthy children with gingivitis and hemodialysis (HD) children with gingivitis.

Methods: A total of 20 children, ages 11â€“16-year-old with gingivitis, were chosen as subjects; 10 were on HD and 10 were healthy children. The level of salivary leptin was measured using the enzyme-linked immunosorbent assay method.

Results: The results showed a significant difference of salivary leptin levels between the children on HD (61,300 Â± 4151 pg/ml) and the healthy children (57,200 Â± 3173 pg/ml).

Conclusions: There is a significant difference in the salivary leptin levels in children on HD with gingivitis and healthy children with gingivitis.

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