DESCRIPTION OF TESTIS HISTOLOGY OF MUS MUSCULUS AFTER GIVING NANO HERBAL RHODOMYRTUS TOMENTOSA (HARAMONTING)

  • Putri Cahaya Situmorang Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan, 20155, Indonesia.
  • Syafruddin Ilyas Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan, 20155, Indonesia.

Abstract

Objective: The objective of this study was to determine the description of testis histology of male mice (Mus musculus) after giving nano-Rhodomyrtus tomentosa (haramonting).

Methods: Leaves of R. tomentosa (haramonting) are made into nanoherbal using high-energy milling, treatment of mice in 14 days, then observation of testis histology, and the data processed with SPSS 22 program with Kruskal–Wallis test.

Results: Nano-R. tomentosa administration was not significantly different in weight of testes (p>0.05), but there was significant difference in Spermatogonia, Spermatocytes, and spermatid.

Conclusions: Nano-R. tomentosa (haramonting) with excessive doses can cause damage of testis cells, interfere with the process of spermatogenesis, and make infertile.

Keywords: Nanotechnology, Nano herbal, Rhodomyrtus tomentosa, Spermatogonia, Spermatocytes, Spermatid.

Author Biographies

Putri Cahaya Situmorang, Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan, 20155, Indonesia.
Department of Biology, Faculty of Mathematics and Natural Sciences
Syafruddin Ilyas, Department of Biology, Faculty of Mathematics and Natural Sciences, Universitas Sumatera Utara, Medan, 20155, Indonesia.
Department of Biology, Faculty of Mathematics and Natural Sciences

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Cahaya Situmorang, P., and S. Ilyas. “DESCRIPTION OF TESTIS HISTOLOGY OF MUS MUSCULUS AFTER GIVING NANO HERBAL RHODOMYRTUS TOMENTOSA (HARAMONTING)”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 11, no. 11, Nov. 2018, pp. 460-3, doi:10.22159/ajpcr.2018.v11i11.29042.
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