TO ESTIMATE THE LEVELS OF CA19-9 AND ITS SIGNIFICANCE IN DIAGNOSIS AND TREATMENT OF PANCREATICOBILIARY AND GASTROINTESTINAL MALIGNANCIES

Authors

  • DEEPANSHI MITTAL JR 2nd year
  • JASVIR SINGH -
  • MANINDER KAUR -
  • ASHWANI KUMAR Department of Biochemistry, Government Medical College and Rajindra Hospital, Patiala, Punjab, India.
  • ANJLEEN KAUR Department of Surgery, Government Medical College and Rajindra Hospital, Patiala, Punjab, India.

DOI:

https://doi.org/10.22159/ajpcr.2022.v15i5.44365

Keywords:

CA19-9, Pancreaticobiliary carcinoma, Metastatic disease

Abstract

Objective: This study was designed and conducted to establish the relationship of biomarker CA19-9 levels in pancreaticobiliary and gastrointestinal malignancies.

Methods: 50 patients with confirmed diagnosis of pancreaticobiliary and gastrointestinal malignancies and 30 age and gender matched controls were included in the study. Serum values of CA19-9 were determined in patients before surgery and chemotherapy.

Results: In our present study, maximum number of patients were in the age group of 51–60 years. Mean levels of serum CA19-9 in patients (n=50) are 146.28±156.87 U/mL. Total patients (n=50), in 19 patients CA19-9 levels were ≤37 U/mL and in 31 patients CA19-9 levels were >37 U/mL. CA19-9 levels were highest in pancreatic and cholangiocarcinoma.

Conclusion: High sensitivity and specificity of CA19-9 in pancreatic and biliary tract tumors identified CA19-9 as a best validated biomarker.

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Published

07-05-2022

How to Cite

MITTAL, D., J. SINGH, M. KAUR, A. KUMAR, and A. KAUR. “TO ESTIMATE THE LEVELS OF CA19-9 AND ITS SIGNIFICANCE IN DIAGNOSIS AND TREATMENT OF PANCREATICOBILIARY AND GASTROINTESTINAL MALIGNANCIES”. Asian Journal of Pharmaceutical and Clinical Research, vol. 15, no. 5, May 2022, pp. 125-7, doi:10.22159/ajpcr.2022.v15i5.44365.

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