A STUDY ON ANTIBIOTIC PRESCRIBING PATTERN IN OBSTRUCTIVE LUNG DISEASE INPATIENTS
Objectives: The main objectives of this study were to estimate the demographic details of patients with obstructive lung disease and to study the
various organisms causing exacerbations and its resistance pattern and also to analyze the culture and sensitivity pattern in obstructive lung disease
Methods: It was a retrospective, observational study carried out for 1 year at the Department of Pulmonary Medicine of a tertiary care teaching
hospital in Kerala, India. Total 200 patients who were admitted under the pulmonary ward during the time period from 1
and who satisfied the inclusion and exclusion criteria were included in the study. A standardized data collection form was prepared, and necessary
data were collected from patientâ€™s medical records.
Results: The maximum number of patients was in the age group of 60â€‘69. 61% patients were residing in the urban area. 32.5% of patients were found
to have a history of smoking. 61% patients were diagnosed with the chronic obstructive pulmonary disease (COPD). 74.5% sample collected were
sputum. Culture test alone was carried out for 48.5%. 88% were prescribed with cephalosporin. Among the cephalosporin class cefpodoxime was the
most commonly prescribed (63%). 42 patients had two drug therapy.
Conclusion: A periodic study on the usage of antibiotics and sensitivity pattern in the hospital will enable the health care professionals to select the
appropriate one to promote the rational use of antibiotics.
Key words: Asthma, Chronic obstructive pulmonary disease, Exacerbation, Antibiotics.
June 2013 to 1
1. Hogg JC, Macklem PT, Thurlbeck WM Site and nature of airway
obstruction in chronic obstructive lung disease. N Engl J Med
2. Walker R, Whittlesea C. Clinical Pharmacy and Therapeutics.
Edinburgh: Churchill Livingstone Elsevier; 2012.
3. Dipiro JT, Talbert RL, Ye GC, Matzke GR, Wells BG, Posey LM.
Pharmacotherapy, A Pathophysiologic Approach. New York: McGraw
4. Erkan L, Uzun O, Findik S, Katar D, Sanic A, Atici AG. Role of bacteria
in acute exacerbations of chronic obstructive pulmonary disease. Int J
Chron Obstruct Pulmon Dis 2008;3(3):463â€‘7.
5. Iikura M, Hojo M, Koketsu R, Watanabe S, Sato A, Chino H, et al. The
importance of bacterial and viral infections associated with adult asthma
exacerbations in clinical practice. PLoS One 2015;10(4):e0123584.
6. James AL, Palmer LJ, Kicic E, Maxwell PS, Lagan SE, Ryan GF,
et al. Decline in lung function in the Busselton Health Study: The
effects of asthma and cigarette smoking. Am J Respir Crit Care Med
7. Gilliland FD, Islam T, Berhane K, Gauderman WJ, McConnell R,
Avol E, et al. Regular smoking and asthma incidence in adolescents.
Am J Respir Crit Care Med 2006;174:1094â€‘100.
8. Laniadoâ€‘LaborÃn R. Smoking and chronic obstructive pulmonary
disease (COPD). Parallel epidemics of the 21 century. Int J Environ Res
Public Health 2009;6:209â€‘24.
9. Bhide A, Munisekhar K, Hemalatha D, Gouroju SK. Pulmonary
function tests in petrol pump workers in Chittoor district. Am J Respir
Crit Care Med 2005;171:109â€‘14.
10. Diette GB, Dalal AA, Dâ€™Souza AO, Lunacsek OE, Nagar SP. Treatment
patterns of chronic obstructive pulmonary disease in employed adults in
the United States. Int J Chron Obstruct Pulmon Dis 2015;10:415â€‘22.
11. Cydulka RK, McFadden ER Jr, Emerman CL, Sivinski LD, Pisanelli W,
Rimm AA. Patterns of hospitalization in elderly patients with asthma
and chronic obstructive pulmonary disease. Am J Respir Crit Care Med
12. Pinal DP, Patel RK, Patel NJ. Analysis of prescription pattern and drug
utilization in asthma therapy. IRJP 2012;3:258â€‘60.
13. LÃ¸kke A, Lange P, Scharling H, Fabricius P, Vestbo J. Developing
COPD: A 25 year follow up study of the general population. Thorax
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