• Sonny Prasetyo Wardojo Department of Conservative Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia.
  • Ratna Meidyawati Department of Conservative Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia.
  • Munyati Usman Department of Conservative Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta, Indonesia.


Objectives: The purpose of this study is to evaluate the influence of grape seed extract (GSE) solution as dentin biomodification on microleakage
between composite resin and dentin.
Methods: A total of 52 dentin specimens were divided into two groups. Group 1 involved the application of GSE solution for 30 seconds after etching.
Group 2 served as the control group.
Results: The GSE solution group significantly increases microleakage between the composite resin and dentin compared to the control group.
Conclusions: The application of GSE solution after etching can increase microleakage between composite resin and dentin.

Keywords: Microleakage, Dentin, Composite, Grape seed extract solution.


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How to Cite
Wardojo, S. P., Meidyawati, R., & Usman, M. (2017). INFLUENCE OF GRAPE SEED EXTRACT SOLUTION ON MICROLEAKAGE BETWEEN COMPOSITE RESIN AND DENTIN. International Journal of Applied Pharmaceutics, 9, 17-19.
Original Article(s)