CRYPTOSOMES: A REVOLUTIONARY BREAK THROUGH IN NOVEL DRUG DELIVERY


Aiswarya M. U., Keerthana Raju, Revathy B. Menon, Lakshmi V. S., Sreeja C. Nair

Abstract


The vesicular drug delivery systems are promising approaches to over thrown the problems of drugs having lesser bioavailability and rapid elimination from the body.  The four type of lipid based drug delivery systems are: solid- lipid particulate system, emulsion based system, solid lipid tablet and vesicular system. Cryptosomes, a novel emerging vesicular drug delivery system which can overcome the disadvantages associated with conventional drug delivery systems like high stability, increased bioavailability, sustained release, decreased elimination of rapidly metabolisable drugs etc. The word Cryptosome was orginated from Greek word ‘’Crypto’’ means hidden and ‘’Soma’’ means body. It is formed from the mixture of phospholipids like distearoyl phosphatidyl ethanolamine- polyethylene glycol (DSPE-PEG) with distearoylphosphatidylcholine. These entire information  regarding its origin and formation is explained in Dinesh Kumar et al. Vesicular systems symbolises the use of vesicles in the different fields as carrier system or additives. This review disclose various vesicular drug delivery system and point out the advancement of cryptosome in the world of drug delivery.


Keywords


Vesicular system; liposome; phospholipids; poloxamer

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