COST-EFFECTIVENESS ANALYSIS OF CEFTRIAXONE GENERIC AND PATENT IN CHILDREN WITH TYPHOID
Objective: This study aimed to measure and compare the effectivity and cost of the two types of ceftriaxone to determine the more cost-effective
Methods: In a cross-sectional analytical study, prescription and administrative financial data were retrospectively collected using the total sampling
method. Data of 63 patients, comprising 43 and 20 patients treated with generic and patent ceftriaxone, respectively, were analyzed. The effectiveness
of the treatment was measured in terms of the length of hospital stay of the patients. The total cost of the treatment was the total median of the costs
of drugs, laboratory examinations, medical device usage, physician service, and hospitalization.
Results: The effectiveness of both generic and patent ceftriaxone was 4 days of hospital stay. Cost-effectiveness ratio of generic ceftriaxone was Rp
575,937.25/day and that of patent ceftriaxone was Rp 888,601.75/day.
Conclusion: Generic ceftriaxone was more cost-effective than patent ceftriaxone.
2. Indonesian Ministry of Health. Indonesian Health Insurance
Organization revival momentum of pharmacoeconomics. Jakarta:
Indonesian Ministry of Health; 2014. Available from: http://www.
ekonomi/#.WLJeef4e3YE. [Last accessed on 2018 Jan 05].
3. Virginia N. Cost-Effectiveness Analysis of Generic Ondansetron with
Logos and Trademarks on Breast Cancer Patients with Moderate
Emetogenic Chemotherapy at Dharmais Cancer Hospital in 2012.
Depok: Universitas Indonesia; 2010.
4. Sudigdo. Basics of Clinical Research Methods. Jakarta: Binarupa
5. Indonesian Ministry of Health. Guidelines for Implementing
Pharmacoeconomic Studies. Jakarta: Indonesian Ministry of Health;
6. Indonesian Ministry of Health. Systematics Guidelines for Controlling
Typhoid Fever. Jakarta: Indonesian Ministry of Health; 2013.
7. Trask LS. Pharmacoeconomics: Principles, methods, and applications. In: Pharmacotherapy: A Patophysiologic Approach. 8th ed. New York
(NY): The McGraw-Hill Companies, Inc.; 2011. p. 1-3.
8. Kurian A, Aswini V, Shiva RB, Jerry DM, Rama P, Vinoth V. A study on
antimicrobial sensitivity and cost analysis of antibiotics in pediatric unit
at a tertiary care hospital. Asian J Pharm Clin Res 2018;11:242-51.
9. Nimin P, Santhosh KV. A comparative study on drug use of antimicrobial
agents in medical and surgical intensive care units of a tertiary care
hospital. Asian J Pharm Clin Res 2018;11:310-3.
10. Miraci M, Haloci E, Toto B. The evaluation of rational use of some
drugs in Albania. Asian J Pharm Clin Res 2015;8:90-4.