MONITORING OF ANTICONVULSANT DRUG SIDE EFFECTS IN OUTPATIENTS WITH EPILEPSY

  • Santi Purna Sari Clinical Pharmacy Laboratory, Faculty of Pharmacy, Universitas Indonesia, Depok 16424, Indonesia.
  • Natasha Kurnia Salma S Clinical Pharmacy Laboratory, Faculty of Pharmacy, Universitas Indonesia, Depok 16424, Indonesia.
  • Alfina Rianti Pharmacy Division, Fatmawati Hospital, Jakarta 12430, Indonesia.

Abstract

Objective: This study aimed to monitor the side effects of carbamazepine, phenytoin, and valproic acid, and combinations of these drugs in adult
patients with epilepsy, to raise awareness of the importance of drug side effect monitoring in hospitals.
Methods: In this prospective study, descriptive data were collected from patients who met the inclusion criteria of complete samples. Primary data
were obtained using questionnaires, secondary data were collected from medical records, and analyses were performed using the Naranjo algorithm.
Results: Among the 54 included patients, 38 (70.37%) of them experienced drug side effects, and the most frequently observed side effect occurred
in 48.15% of study subjects.
Conclusion: No correlation was identified between side effects and age (p=0.903) or gender (p=1.000).

Keywords: Carbamazepine, Naranjo algorithm, Phenytoin, Side effects, Valproic acid.

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How to Cite
Sari, S. P., Salma S, N. K., & Rianti, A. (2018). MONITORING OF ANTICONVULSANT DRUG SIDE EFFECTS IN OUTPATIENTS WITH EPILEPSY. International Journal of Applied Pharmaceutics, 10(1), 303-306. https://doi.org/10.22159/ijap.2018.v10s1.67
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Original Article(s)