SILVER NANOPARTICLES AND COCONUT OIL INCORPORATED BIOPOLYMER BASED ELECTROSPUN NANOFIBERS FOR WOUND DRESSING
The main aim of this study was to develop and evaluate the nanofiber loaded with coconut oil and silver nanoparticles (Ag NPs) for the treatment of wound healing by electro spun method. The silver nanoparticles are considered as a prominent bio material which can bring about anti-microbial properties and anti-bacterial activity. Hence, this can help us to formulate a Eudragit L-100/silver NPs based nanofibers for the purpose of wound healing. The electrospin nanofibers are light in weight, ranging from a nanometer to excess of 100 nm. Different evaluation parameters like Fourier Transform Infrared (FTIR), X-ray diffraction (XRD), hydrophilicity test, biocompatibility of complex mixture and bactericidal activity of the electro spun fibers have been evaluated. The nanofibers are created using reduced form of silver nanoparticles and coconut oil along with Eudragit L-100 by the electrospin method. The morphological studies are carried out for the nanofibers along with chemical investigation of wound curing. The electrospin nanofibers are carried out for wetting investigation and in-vitro cytotoxicity test. The bactericidal activity has been carried out for zone of inhibition between Escherichia coli and Staphylococcus aureus. The formulated nanofibers offer protection against external agents and help in regeneration of new tissue.
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