ISOLATION AND CHARACTERISATION OF ANTI-BACTERIAL RESISTANCE PATTERNS OF BACTERIAL ISOLATES FROM URINARY TRACT INFECTION IN DIABETICS
Abstract
Objective: Urinary tract infection (UTI) is one of the most common infections observed in diabetic patients. This study is aimed at identifying the organisms with their anti-bacterial resistance pattern.
Methods: A total of 400 diabetic patients over a period of nine months presenting with symptom s of urinary tract infection were taken for the study. Their urine were cultured and an antibiogram done.
Results: E. coli, Klebsiella and Enterococci were the commonest organism found. It was found that E. coli, which was the commonest organism E. Coli was sensitive to Norfloxacin and resistant to Ciprofloxacin.
Conclusion: Empirical treatment with ciprofloxacin, Which is considered the drug of choice, will lead to failure of treatment.
References
2. Adeyeba, PO Omosigho, YO Adesiji. Bacterial urinary tract infections in patients with diabetes mellitus. Int J Trop Med 2007;2:89-2.
3. Goswami R, Bal CS, Tejaswi S, Punjabi GV, Kapil A, Kochupillai N. Prevalence of urinary tract infection and renal scars in patients with diabetes mellitus. Diab Res Clin Pract 2001;53:181-6.
4. Lloyds S, Zervas M, Mahayni R, Lundstrom T. Risk factors for enterococal urinary tract infection and colonization in a rehabilitation facility. Am J Infect Control 1998;26:35-9.
5. World Health Organization: Definition, Diagnosis and Classification of diabetes mellitus and its complications; Part 1: Diagnosis and Classification of diabetes mellitus, Geneva. Department of non communicable Disease Surveillance. WHO; 1999.
6. Bonadio M, Costarelli S, Morelli G, Tartaglia T. The influence of diabetes mellitus on the spectrum of uropathogens and the antimicrobial resistance in elderly adult patients with urinary tract infection. BMC Infect Dis 2006;6:54.
7. Bashir MF, JI Qazi, N Ahmed, S Riaz. Diversity of urinary tract pathogens and drug-resistant isolates of Escherichea coli in different age and gender groups of Pakistanis. Trop J Pharm Res 2008;7:1025-31.
8. Bhatia JK, Mathur AD, Arora MM. Reemergence of chloramphenicol sensitivity in enteric fever. Med J Armed Forces India 2007;63:212–4.
9. Bauer AW, Kirby WMM, Sherris JC, Turck M. Antibiotic susceptibility testing by a standardised singles disk method. Am J Clin Pathol 1966;45:493-6.
10. Akhtar S, Sarker MR, Jabeen K, Sattar A, Qamar A, Fasih N. Antimicrobial resistance in Salmonella enterica serovar typhi and paratyphi in South Asia—current status, issues and prospects. Crit Rev Microbiol 2015;41:536–45.

This work is licensed under a Creative Commons Attribution 4.0 International License.