TOTAL FLAVONOID CONTENT AND ANTIMICROBIAL PROPERTIES OF FOUR SPECIES OF ZINGIBERACEAE


Rika Hartati, Asep Gana Suganda, Irda Fidrianny, Theresia Monica Ginting

Abstract


Objectives: The objectives of this research were to study flavonoid content and antimicrobial activity of four species of Zingiberaceae plants that were collected randomly in West Java (Indonesia).

Methods: Preparation of extract were perfomed by reflux using ethanol as a solvent. The extracts were vaporated using rotavapor. Total flavonoid content was measured using modified method adapted from Chang. For antimicrobial activity microdilution broth method was used.

Results: Antimicrobial activity of four Zingiberaceae plants showed various potency. Hornstedtia pininga, Amomum hochreutineri and Hedychium roxburghii showed strong activity against Bacilus subtilis (MIC at 500 μg/mL). The strongest activity against E. coli were showed by H. pininga and H. roxburghii the MIC were 31.25 μg/mL. Whereas, the strongest antimicrobial activity against P. aeruginosa was H. roxburghii (MIC was 62.5 μg/mL). In line with total flavonoid content results, the highest yield was obtained by H. roxburghii rhizome extract (0.162%), followed by A. hochreutineri (0.76%), Nicolaia hemisphaerica (0.071%) and H. pininga (0.04%).

Conclusion: In the present study, ethanolic extract of four Zingiberaceae showed an antimicrobial activity with various potency. Hornstedtia pininga, Amomum hochreutineri and Hedychium roxburghii showed strong activity against Bacilus subtilis (MIC at 500 μg/mL).

Keywords: Zingiberaceae, Flavonoid, Antimicrobial, Hedychium, Hornstedtia.


Keywords


Zingiberaceae, Flavonoid, Antimicrobial, Hedychium, Hornstedtia.

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About this article

Title

TOTAL FLAVONOID CONTENT AND ANTIMICROBIAL PROPERTIES OF FOUR SPECIES OF ZINGIBERACEAE

Keywords

Zingiberaceae, Flavonoid, Antimicrobial, Hedychium, Hornstedtia.

Date

28-07-2014

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 6, Issue 7, 2014 Page: 142-148

Online ISSN

0975-1491

Authors & Affiliations

Rika Hartati
School of Pharmacy Bandung Institute of Technology
Indonesia

Asep Gana Suganda
School of Pharmacy Bandung Institute of Technology
Indonesia

Irda Fidrianny
School of Pharmacy Bandung Institute of Technology

Theresia Monica Ginting
School of Pharmacy Bandung Institute of Technology
Indonesia


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