• Harsh Arora Amity University
  • Nidhi Srivastava Amity University
  • Kumud Bala Amity University


Objective: The current study was carried out to assess the prevalence of vitamin D/B12 deficiency among urban populations complaining pain of
lower limb and generalize weakness.
Methods: A cross-sectional study was conducted in a sample of 188 men and women of different age who attended private tertiary care hospital for
the complaint of pain in lower limb and have generalize weakness. A brief questionnaire was designed to obtain the information such as age, type of
diet, outdoor physical exercise and intake of alcohol or smoke. Blood samples were collected for vitamin D and B12 analysis.
Results: The majority (57.4%) of the participants had vitamin D deficiency or insufficiency (< 20 ng/ml) and 48.4 % of subjects had vitamin B12
deficiency (< 198 pg/ml). In our results the prevalence of both vitamin D/B12 deficiencies appears to increase with the age. Risk factors such as age,
diet and smoke (cigarette consumption) were significantly associated with vitamin D/B12 deficiency (p=0.001). Unlike vitamin B12, outdoor physical
exercise was significantly associated with vitamin D status (p=0.001).
Conclusion: The findings of this study report high prevalence of vitamin D/B12 deficiencies among urban populations complaining pain of lower limb
and have generalize weakness. A vegetarian diet, cigarette smoking seems a strong risk factor for vitamin D/B12 deficiencies. Our study emphasizes
the need of regular monitoring of these two micronutrient status so that appropriate intervention programs can be implemented to address this
Keywords: Vitamin D, Vitamin B12, India.


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How to Cite
Arora, H., N. Srivastava, and K. Bala. “PREVALENCE OF VITAMIN D/B12 DEFICIENCY AMONG URBAN POPULATIONS COMPLAINING PAIN OF LOWER LIMB AND GENERALIZE WEAKNESS”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 9, no. 3, May 2016, pp. 261-3,
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