VANCOMYCIN INTERMEDIATE AND VANCOMYCIN RESISTANT STAPHYLOCOCCUS AUREUS – MECHANISMS, CLINICAL SIGNIFICANCE AND DETECTION


Gopalkrishna K Bhat, Jyoti Kumari, Shalini M Shenoy, Ashwini Hegde, Chakrapani M, Vidyalakshmi K

Abstract


Vancomycin is used as the antibiotic of choice for severe infection caused by methicillin resistant Staphylococcus aureus. Increased use of vancomycin and the selective pressure has resulted in the emergence of S.aureus with reduced susceptibility to vancomycin and vancomycin resistant S.aureus. This review summarizes the definition, mechanism, clinical significance and epidemiology of S.aureus with reduced susceptibility to vancomycin. It also discusses laboratory methods for detection and treatment options available for these pathogens.


Keywords


Vancomycin, Vancomycin intermediate Staphylococcus aureus, Heteroresistant vancomycin intermediate Staphylococcus aureus, Vancomycin resistant Staphylococcus aureus

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About this article

Title

VANCOMYCIN INTERMEDIATE AND VANCOMYCIN RESISTANT STAPHYLOCOCCUS AUREUS – MECHANISMS, CLINICAL SIGNIFICANCE AND DETECTION

Keywords

Vancomycin, Vancomycin intermediate Staphylococcus aureus, Heteroresistant vancomycin intermediate Staphylococcus aureus, Vancomycin resistant Staphylococcus aureus

DOI

10.22159/ajpcr.2017.v10i6.15993

Date

01-06-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 6 June 2017 Page: 32-38

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

148 Views | 117 Downloads

Authors & Affiliations

Gopalkrishna K Bhat
Department of Microbiology, Kasturba Medical College, Mangalore, Karnataka, India
India

Jyoti Kumari
Department of Microbiology, Kasturba Medical College, Mangalore, Karnataka, India
India

Shalini M Shenoy
Department of Microbiology, Kasturba Medical College, Mangalore, Karnataka, India
India

Ashwini Hegde
Department of Microbiology, Kasturba Medical College, Mangalore, Karnataka, India
India

Chakrapani M
Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India.
India

Vidyalakshmi K
Department of Microbiology, Kasturba Medical College, Mangalore, Karnataka, India
India


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