BORTEZOMIB INDUCED SUBCONJUNCTIVAL HEMORRHAGE


Navin Patil, Balaji Ommurugan, Karthik S Udupa, Karthik Rao

Abstract


Many drugs are used in the treatment of multiple myeloma but Thalidomide, Lenalidomide, Bortezomib, dexamethasone and their combination remains the main stay of treatment. The molecular formula of bortezomib is C19H25BN4O4 and its chemical IUPAC name is [3-methyl-1-(3-phenyl-2-pyrazin-2-ylcarbonylamino-propanoyl) amino-butyl] boronic acid. Mechanisms by which it acts is usually by 26 SProteasome inhibition leading to degradation of anti-apoptotic proteins. Bortezomib is known to cause many side effects. So hence we report a rare case of Bortezomib induced subconjunctival hemorrhage in our tertiary care hospital.

KEYWORDS: Bortezomib, Adverse effect, Proteosome inhibition, Subconjunctival Hemorrhage


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References


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About this article

Title

BORTEZOMIB INDUCED SUBCONJUNCTIVAL HEMORRHAGE

DOI

10.22159/ajpcr.2017.v10i4.16907

Date

01-04-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 10 Issue 4 April 2017 Page: 10-11

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

152 Views | 136 Downloads

Authors & Affiliations

Navin Patil
Assistant Professor , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
India

Balaji Ommurugan
Post graduate, Department of Pharmacology, Kasturba Medical College, Manipal University ,Manipal.
India

Karthik S Udupa
Associate Professor, department of Medical oncology, Kasturba Medical college, Manipal University,Manipal.
India

Karthik Rao
Assistant Professor, Department of Internal Medicine, KASTURBA MEDICAL COLLEGE, Manipal.
India


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