Rabeprazole induced Fixed Drug Eruption: A rare case report

  • Balaji Ommurugan Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
  • Amita Priya Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
  • Navin Patil ASSISTANT PROFESSOR , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.

Abstract

Among cutaneous adverse drug reactions, fixed drug eruption is the most common cutaneous drug reaction among the Indian population. The drugs
most commonly implicated in fixed drug eruption are analgesics and antibiotics. Here, we report a case of fixed drug reaction caused by rabeprazole.

   


Keywords: Fixed drug eruption, Rabeprazole, Proton-pump Inhibitor, Naranjo’s scale.

References

1.Breathnach SM. Adverse Cutaneous reactions to drugs. Clin Med 2002; 2: 15–9. 2.
2.Hiware S, Shrivastava M, Mishra D, Mukhi J, Puppalwar G. Evaluation of Cutaneous Drug Reactions in Patients Visiting Out Patient Departments of Indira Gandhi Government Medical College and Hospital (IGGMC and H), Nagpur. Indian J Dermatol 2013 Jan-Feb; 58(1): 18–21.
3. Benedix F, Schilling M, Schaller M, Röcken M, Biedermann T. A Young Woman with Recurrent Vesicles on the Lower Lip: Fixed Drug Eruption Mimicking Herpes Simplex. Acta Derm Venereol 2008; 88: 491–49
4.Breathnach SM. Drug Reactions. In: DABurns, SM Breathnach, NH Cox, CEM Griffiths, editors. Rook's Textbook of Dermatology. 8th ed., West Sussex: Blackwell Publishing Ltd; 2010. p. 75.1-75.177.
5. Anjay R Patel, Priyal R Patel, Chintan N Vora, Nitin D Patel, Jayvadan K Patel
Formulation, process parameters optimization and evaluation of delayed release tablets
Of rabeprazole sodium. Int J Pharmacy Pharm Sci 2010; 2(3):144-56.
6.Kepekci Y, Kadayifci A. Fixed drug eruption in hands caused by omeprazole. Int J Clin Pharmacol Ther 1999 Jun; 37(6): 307-9.
7. Kai Y, Okamoto O, Fujiwara S. Fixed drug eruption caused by three unrelated drugs: promethazine, pethidine and omeprazole. Clin Exp Dermatol 2011 Oct; 36(7): 755-8.
8. Morais P, Baudrier T, Mota A, Cunha AP, Cadinha S, Barros AM et.al. Nonpigmented fixed drug eruption induced by esomeprazole. Cutan Ocul Toxicol 2010 Sep; 29(3): 217-20.
9. Savin JA. Current causes of fixed drug eruption in the UK. Br J Dermatol 2001; 145: 667–8.
10. Balaji O, Navin P, Avinash A, Amod T. Cefuroxime-induced thrombocytopenia: it’s just not in the ring? Asian J Pharms Clin Res. 2016;9(5): 1-2.
Statistics
494 Views | 466 Downloads
Citatons
How to Cite
Ommurugan, B., A. Priya, and N. Patil. “Rabeprazole Induced Fixed Drug Eruption: A Rare Case Report”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 5, May 2017, pp. 13-14, doi:10.22159/ajpcr.2017.v10i5.17123.
Section
Case Study(s)

Most read articles by the same author(s)

1 2 > >>