SALIVARY SECRETORY IMMUNOGLOBULIN A LEVEL OF CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA IN MAINTENANCE PHASE

Authors

  • Danar Pradipta Rani Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.
  • Sarworini B Budiardjo Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.
  • Margaretha Suharsini Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i3.23261

Keywords:

Acute lymphoblastic leukemia, Salivary secretory immunoglobulin A, Gingivitis, Maintenance phase

Abstract

 Objective: The objective of this research is to investigate the differences in salivary secretory immunoglobulin A (sIgA) levels between children with gingivitis who have acute lymphoblastic leukemia (ALL) and are in the maintenance phase of chemotherapy and the levels in healthy children with gingivitis.

Methods: This study used cross-sectional and laboratory observation methods with 19 ALL children and 19 healthy children who all had mild gingivitis. Two mL of saliva were collected and stored at −200°C. Then, salivary sIgA levels were measured using the ELISA method.

Results: The results indicate an insignificant difference (p>0.05) in salivary sIgA levels between the ALL children in the maintenance phase with the level of 21.38 (7.23–107.26) and 37.26 (11.24–135.63) for the healthy children.

Conclusion: There is no significant difference in salivary sIgA levels between the ALL children in the maintenance phase and the healthy children.

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Author Biographies

Danar Pradipta Rani, Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.

department of pediatric dentistry

Sarworini B Budiardjo, Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.

department of pediatric dentistry

Margaretha Suharsini, Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.

department of pediatric dentistry

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Published

01-03-2018

How to Cite

Rani, D. P., S. B. Budiardjo, and M. Suharsini. “SALIVARY SECRETORY IMMUNOGLOBULIN A LEVEL OF CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA IN MAINTENANCE PHASE”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 3, Mar. 2018, pp. 50-52, doi:10.22159/ajpcr.2018.v11i3.23261.

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Original Article(s)