• Agnes Linggriani Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.
  • Mochamad Fahlevi Rizal Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.
  • Eva Fauziah Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.
  • Margaretha Suharsini Department of Pediatric Dentistry, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.




Flavonoid, Propolis, Streptococcus mutans, Biofilm, Crystal violet


 Objective: This study was conducted to analyze the effects obtained with different concentrations (0.5 and 0.1%) of propolis flavonoids on in vitro biofilm formation by clinical Streptococcus mutans strains isolated from children's dental plaque.

Materials and Methods: S. mutans isolated from children's dental plaque was assayed for biofilm formation in 96-microwell plates using crystal violet.

Results: The effects on S. mutans biofilm formation were the same for propolis flavonoids administered at concentrations of 0.05 and 0.1% (p>0.01).

Conclusion: A 0.05% propolis flavonoids concentration was deemed as effective as a 0.1% concentration at inhibiting S. mutans biofilm formation.


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How to Cite

Linggriani, A., M. F. Rizal, E. Fauziah, and M. Suharsini. “DIFFERENCES IN THE EFFECTS OF 0.05% AND 0.1% PROPOLIS FLAVONOIDS ON IN VITRO BIOFILM FORMATION BY STREPTOCOCCUS MUTANS FROM CHILDREN’S DENTAL PLAQUE”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 2, Feb. 2018, pp. 215-8, doi:10.22159/ajpcr.2018.v11i2.22521.



Original Article(s)