CORRELATION BETWEEN PHYTOESTROGENS INTAKE WITH TELOMERE LENGTH IN MINANGKABAU PREMENOPAUSAL WOMEN
Keywords:Phytochemical, Phytoestrogens, Telomere, Estradiol, Premenopausal, Minangkabau
Objective: This study aimed to investigate the correlation between phytoestrogens intake with telomere length in premenopausal Minangkabau ethnicity women.
Methods: This cross-sectional study was conducted in Padang city, to 113 premenopausal Minangkabau ethnic 40â€“54 years old. Food intake data were obtained by an interview by trained enumerators using semi-quantitative food frequency questionnaire. Telomere examination was done from 3 ml of venous blood. Telomere length examination by modification of O'Callaghan and Fenech method. Estradiol level was measured by the ELISA technique.
Results: This research indicated an average telomere length was 554.79Â±426.81 bp, estradiol level was 149.47Â±52.26 pg/ml, and phytoestrogens intake was 37.95Â±32.25 mg/day. There were the differences between phytoestrogens intake and telomere length based on estradiol levels. Then, there was no significant correlation between phytoestrogens intake and telomere length.
Conclusion: There is no significant positive correlation between phytoestrogens intake and telomere length of premenopausal women in the Minangkabau ethnic.
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