A REVIEW: FLOATING DRUG DELIVERY SYSTEM AS A TOOL TO IMPROVE DISSOLUTION RATE IN GASTRIC

  • IYAN SOPYAN Study Center of Drug Discovery and Drug Development, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363 Indonesia, Departemant of Pharmaceutics and Technology of Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia
  • SRIWIDODO Departemant of Pharmaceutics and Technology of Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia
  • RETNO WAHYUNINGRUM Department of Pharmacy, Faculty of Science and Technology, Universitas Sembilanbelas November, Kolaka, 93517, Indonesia
  • NORISCA ALIZA P. Departemant of Pharmaceutics and Technology of Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, 45363, Indonesia

Abstract

Floating drugs are an effective way to lift the absorption of the drug in the stomach. Drugs made drugs last longer in the stomach so that the solubility process will occur effectively in the stomach. This review-journal was created by extracting indexed journals with the floating drug as journal keywords of 40 journals. This assessment of a floating drug for a new drug delivery system (NDDS) is established to elucidate the floating drugs delivery system (FDDS) based on existing literature. The most recent progress of FDDS includes the formulation and physiological variables that could affect gastric retention and formulation are dealt with in detail. This review also summarizes some approaches to prepare a floating system, evaluation methods and characterization for FDDS pharmaceutical dosage form and also its classification.

Keywords: Floating drug, Gastric Retentive, Dissolution

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SOPYAN, I., SRIWIDODO, WAHYUNINGRUM, R., & P., N. A. (2020). A REVIEW: FLOATING DRUG DELIVERY SYSTEM AS A TOOL TO IMPROVE DISSOLUTION RATE IN GASTRIC. International Journal of Applied Pharmaceutics, 12(4), 51-54. https://doi.org/10.22159/ijap.2020v12i4.38415
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Review Article(s)