PRELIMINARY PHYTOCHEMICAL SCREENING AND TO EVALUATE ANTI-OXIDANT PROPERTY ON ROOT EXTRACT OF DILLENIA INDICA (ELEPHANT APPLE)

BIDISHA BORDOLOI; SUMIT DAS

doi:10.22159/ijcpr.2019v11i4.34957

Authors

BIDISHA BORDOLOI Department of Pharmaceutical Sciences, Girijananda Chowdhury Institute of Pharmaceutical Science (GIPS), Azara, Hatkhowapara, NH-37, Guwahati, Assam 781017
SUMIT DAS Department of Pharmaceutical Sciences, Girijananda Chowdhury Institute of Pharmaceutical Science (GIPS), Azara, Hatkhowapara, NH-37, Guwahati, Assam 781017

DOI:

https://doi.org/10.22159/ijcpr.2019v11i4.34957

Keywords:

Phytochemical screening, Pharmacognostic evaluation, Anti-oxidant activity

Abstract

Objective: The objective of the present study was to carry out the presence of antioxidants activity on root extract of Dilleniaindica (Family-Dilleniaceae) which is believed to have the protective mechanisms in beneficial health effects.

Methods: Considering its medicinal importance, the plant was chosen for extraction with various solvents such as petroleum ether, chloroform and ethanol which was taken into considerations to determine the phytochemicals analyses present in it. The extracts of the roots were evaluated for antioxidant activity by using different in vitro models like Reducing Power method, TBA Method and DPPH method at different doses (20,50,100,200,400μg/ml). The ic50 values of each extract on different activity were carried out.

Results: The study shows that petroleum ether, chloroform and ethanolic extract of this plant showed potent antioxidant activity against the standard drug (Ascorbic acid). But chloroform extract of the roots shown most significant anti-oxidant activity as compared to petroleum ether and ethanol.

Conclusion: The root part of the plant shows active anti-oxidant activity that can be consumed by mankind.

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