PRELIMINARY PHYTOCHEMICAL SCREENING AND TO EVALUATE ANTI-OXIDANT PROPERTY ON ROOT EXTRACT OF DILLENIA INDICA (ELEPHANT APPLE)

  • BIDISHA BORDOLOI Department of Pharmaceutical Sciences, Girijananda Chowdhury Institute of Pharmaceutical Science (GIPS), Azara, Hatkhowapara, NH-37, Guwahati, Assam 781017
  • SUMIT DAS Department of Pharmaceutical Sciences, Girijananda Chowdhury Institute of Pharmaceutical Science (GIPS), Azara, Hatkhowapara, NH-37, Guwahati, Assam 781017

Abstract

Objective: The objective of the present study was to carry out the presence of antioxidants activity on root extract of Dilleniaindica (Family-Dilleniaceae) which is believed to have the protective mechanisms in beneficial health effects.


Methods: Considering its medicinal importance, the plant was chosen for extraction with various solvents such as petroleum ether, chloroform and ethanol which was taken into considerations to determine the phytochemicals analyses present in it. The extracts of the roots were evaluated for antioxidant activity by using different in vitro models like Reducing Power method, TBA Method and DPPH method at different doses (20,50,100,200,400μg/ml). The ic50 values of each extract on different activity were carried out.


Results: The study shows that petroleum ether, chloroform and ethanolic extract of this plant showed potent antioxidant activity against the standard drug (Ascorbic acid). But chloroform extract of the roots shown most significant anti-oxidant activity as compared to petroleum ether and ethanol.


Conclusion: The root part of the plant shows active anti-oxidant activity that can be consumed by mankind.

Keywords: Phytochemical screening, Pharmacognostic evaluation, Anti-oxidant activity

References

1. CP Kala. Current status of medicinal plants used by traditional vaidyas in Uttaranchal state of India. Ethnobot Res Appl 2005;2:267-78.
2. R Capasso, AA Izzo, L Pinto, T Bifulco. Phytotherapy and quality of herbal medicine. Fitoterapia 2000;71 Suppl 1:S58-65.
3. M Tamer, G Sanjay. Traditional knowledge and use of medicinal plants in the eastern desert of Egypt: a case study from. Wadi El-Gemal National Park 2013;1:10-7.
4. K Bisht, RS Rawal, U Dhar. Prioritization and conservation of Himalayan medicinal plants: Angelica glauca Edgew. As a case study. Ethnobot Res Appl 2006;4:11-23.
5. K Kokate, AP Purohit. A textbook of pharmacognosy. Nirali Prakashan; 2014. p. 25.
6. Jose S. Pandiammal. J Academia and Industrial Research; 2016. p. 2278-5213.
7. P Nimse, P Dilipkumar. Free radicals, natural antioxidants, and their reaction mechanism. Institute Appl Chem, Department Chem 2015;5:27986-8006.
8. PR Shankar. Anti-oxidant activity of Dillenia Indica linn. Asian J Pharm Life Sci 2012;2:360-4.
9. MH Abdille, RP Singh, GK Jayaprakasha. Antioxidant activity of the extracts from Dillenia indica fruits. Food Chem 2005;90:891-6.
10. R Arbianti, TS Utami, A Kurmana. Comparison of antioxidant activity and total phenolic content of Dillenia indica leaves extracts obtained using various techniques. Proceedings of the 14th Regional Symposium on Chemical Engineering; 2007;92:851-66.
11. SB Boozer, GS Hammond, CE Hamilton, JN Sen. Air oxidation of hydrocarbons 1II. The stoichiometry and fate of inhibitors in benzene and chlorobenzene. J Am Chem Soc 1995;77:3233-43.
12. MH Abdille, RP Singh, GK Jayaprakasha, BS Jena. Antioxidant activity of the extracts from Dillenia indica fruits. Food Chem 2005;90:891-6.
Statistics
37 Views | 47 Downloads
How to Cite
BORDOLOI, B., and S. DAS. “PRELIMINARY PHYTOCHEMICAL SCREENING AND TO EVALUATE ANTI-OXIDANT PROPERTY ON ROOT EXTRACT OF DILLENIA INDICA (ELEPHANT APPLE)”. International Journal of Current Pharmaceutical Research, Vol. 11, no. 4, July 2019, pp. 128-33, doi:10.22159/ijcpr.2019v11i4.34957.
Section
Original Article(s)