EVALUATION OF ANTIBACTERIAL ACTIVITY OF INDONESIAN VARIETIES SWEET POTATO LEAVES EXTRACT FROM CILEMBU AGAINST Shigella dysenteriae ATCC 13313

  • Sri Agung Fitri Kusuma "Padjadjaran University"

Abstract

Objective: The aim of this study was to evaluate the in Vitro antibacterial  activity of sweet potato (Ipomoea batatas (L.) Lam) leaves ethanol extract  against Shigella dysenteriae ATCC 13313.

Methods: The study was performed by collecting and determining plant samples, extraction, moisture content assay, phytochemical screening, Thin layer Chromatography, antibacterial activity using agar diffusion method using perforator of 11 mm in diameter and Minimum Inhibition Concentration (MIC) test using macrodilution method against Shigella dysenteriae ATCC 13313.

Results: The Phytochemical analysis of the sweet potato leaves extract revealed the presence of  flavonoids, tannin, steroid and polyphenolic compound. The sweet potato leaves ethanol extract showed significant zone of inhibition in a dose dependent manner against Shigella dysenteriae ATCC 13313 with the range of MIC and MBC was 10-20 % b/v.

Conclusion : It can be concluded that the sweet potato leaves ethanol extract  shows promise as an antibacterial agent for inhibiting bacillary dysentery due to the presence of biologically active ingredients with antimicrobial activity in the extract.

Keywords: sweet potato, Cilembu, Indonesia, antidysentery, Shigella dysenteriae ATCC 13313

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Kusuma, S. A. F. “EVALUATION OF ANTIBACTERIAL ACTIVITY OF INDONESIAN VARIETIES SWEET POTATO LEAVES EXTRACT FROM CILEMBU AGAINST Shigella Dysenteriae ATCC 13313”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 2, Feb. 2017, pp. 377-80, doi:10.22159/ajpcr.2017.v10i2.15773.
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