ROLE OF PHARMACISTS IN REDUCING DRUG-RELATED PROBLEMS IN HEMODIALYSIS OUTPATIENTS


Romauli Lumbantobing, Rani Sauriasari, Retnosari Andrajati

Abstract


 

 Objectives: Hemodialysis outpatients have a higher risk of developing drug-related problems. Pharmacists play a key role in identifying and preventing these drug-related problems. This study aimed to assess the effect of pharmacist intervention on the number and types of drug-related problems in outpatients undergoing hemodialysis at Indonesia Christian University Hospital.

Methods: This pre- and post-prospective study was conducted from January 2013 to June 2013. We evaluated 86 patients who were prescribed 804 drugs.

Results: A total of 337 drug-related problems were identified (41.86% of the total drugs prescribed). The types of drug-related problems identified were as follows: Failed therapy (18.69%); sub-optimal therapy (52.23%); indication of non-administration of therapy (2.37%); and non-allergic adverse drug effects (26.71%). The physicians received 59 recommendations, and the patients received 278 recommendations. These recommendations resulted in a decrease in ineffective drug therapy or therapeutic failure (18.69-0%), sub-optimal therapy (52.23-21.36%), indications of non-administration of drug (2.37-2.08%), and non-allergic adverse drug effects (26.71-9.20%). The factors that significantly affected the occurrence of drug-related problems were hemodialysis frequency, number of comorbidities, and number of drugs prescribed. Patients undergoing hemodialysis 3 times a week were more likely to experience a decrease in drug-related problems than those undergoing hemodialysis twice a week (odds ratio 26.33, 95% confidence interval 2.710-255.884).

Conclusions: Pharmacist intervention could decrease drug-related problems in hemodialysis patients.


Keywords


Role of pharmacists, Drug-related problems, PCNE-6.02, Hemodialysis, Outpatient.

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References


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About this article

Title

ROLE OF PHARMACISTS IN REDUCING DRUG-RELATED PROBLEMS IN HEMODIALYSIS OUTPATIENTS

Keywords

Role of pharmacists, Drug-related problems, PCNE-6.02, Hemodialysis, Outpatient.

DOI

10.22159/ajpcr.2017.v10s5.23110

Date

01-10-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol. 10, Special Issue (Oct.), 2017 [PTMDS 2017] Page: 108-113

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

120 Views | 78 Downloads

Authors & Affiliations

Romauli Lumbantobing
Department of Pharmacy, Universitas Kristen Indonesia Hospital, Jakarta, Indonesia
Indonesia

Rani Sauriasari
Department of , Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
Indonesia

Retnosari Andrajati
Department of , Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
Indonesia


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