ROLE OF PHARMACISTS IN REDUCING DRUG-RELATED PROBLEMS IN HEMODIALYSIS OUTPATIENTS


ROMAULI LUMBANTOBING

Abstract


Objectives: Hemodialysis outpatients have a higher risk of developing drug-related problems. Pharmacists play a key role in identifying and preventing
these drug-related problems. This study aimed to assess the effect of pharmacist intervention on the number and types of drug-related problems in
outpatients undergoing hemodialysis at Indonesia Christian University Hospital.
Methods: This pre- and post-prospective study was conducted from January 2013 to June 2013. We evaluated 86 patients who were prescribed 804
drugs.
Results: A total of 337 drug-related problems were identified (41.86% of the total drugs prescribed). The types of drug-related problems identified
were as follows: Failed therapy (18.69%); sub-optimal therapy (52.23%); indication of non-administration of therapy (2.37%); and non-allergic adverse
drug effects (26.71%). The physicians received 59 recommendations, and the patients received 278 recommendations. These recommendations
resulted in a decrease in ineffective drug therapy or therapeutic failure (18.69-0%), sub-optimal therapy (52.23-21.36%), indications of nonadministration
of
drug (2.37-2.08%), and
non-allergic
adverse
drug
effects
(26.71-9.20%). The
factors
that
significantly
affected
the occurrence
of
drug-related
problems
were
hemodialysis
frequency,
number of comorbidities,
and
number of drugs
prescribed.
Patients
undergoing
hemodialysis

3
times
a
week
were
more
likely
to
experience
a
decrease
in
drug-related
problems
than those undergoing
hemodialysis
twice
a week
(odds ratio

26.33,
95% confidence interval
2.710-255.884).
Conclusions: Pharmacist intervention could decrease drug-related problems in hemodialysis patients.


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About this article

Title

ROLE OF PHARMACISTS IN REDUCING DRUG-RELATED PROBLEMS IN HEMODIALYSIS OUTPATIENTS

Date

01-10-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Special Issue October 2017 [PTMDS 2017] Page: 108-113

Print ISSN

0974-2441

Online ISSN

2455-3891

Statistics

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Authors & Affiliations

ROMAULI LUMBANTOBING
Department of Pharmacy, Universitas Kristen Indonesia Hospital, Jakarta, Indonesia
Indonesia


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