THE EFFECT OF DRUG-RELATED PROBLEMS ON THE DECREASE OF HEMOGLOBINE LEVELS IN CANCER PATIENTS
Keywords:Doxorubicin, Drug-related problems, Hemoglobin
Â Objectives: The aim of this study was to determine the effect of drug-related problems (DRPs) on the decrease in hemoglobin levels in cancer patients.
Methods: This study was a prospective cross-sectional study on seven cancer patients at Haji Adam Malik (HAM) Hospital. Patients aged 35 years old and above with any cancer type and stage from April 2017 to July 2017 were included in the study at HAM Hospital Medan. DRPs were analyzed using DRP Registration Form V7.0 Pharmaceutical Care Network Europe. The obtain data were tested using Chi-square test (p<0.05 is considered significant).
Results: The result showed that based on the characteristics of age, the largest group was 46â€“55 years, and based on the suffered stage, the most stage was Stage III with 57.14%. Two DRPs were identified in seven patients. The most prevalent DRPs were the interaction of drug (100%) followed by unwanted drug reaction (85.71%) and the risk of DRPs was decreasing the hemoglobin levels in cancer patients from the median-to-moderate levels.
Conclusion: Drug-related problems are common among cancer patients. Interaction of drug problems and unwanted drug reaction were the most common types of DRPs among cancer patients, and showed that there was a relationship of DRPs on the decrease in hemoglobin levels.
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