EFFICACY OF JAVANESE TURMERIC ETHANOL EXTRACT IN ERADICATING STREPTOCOCCUS SANGUINIS AND PORPHYROMONAS GINGIVALIS BIOFILM

  • REZON YANUAR Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia.
  • DEWI FATMA SUNIARTI Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia
  • WIDURINI DJOHAN Department of Oral Biology, Faculty of Dentistry, Universitas Indonesia, Jakarta 10430, Indonesia

Abstract

Objective: Javanese turmeric is an Indonesian native medicinal plant with antibacterial activities. This study aimed to analyze the efficacy of identified
Javanese turmeric ethanol extract (IJTEE) in eradicating Streptococcus sanguinis and Porphyromonas gingivalis biofilms.
Methods: Biofilm assay: Single and combination biofilms formed at different phases were exposed to IJTEE in 0.5–25% concentrations for 1 h. The
percentage of eradication was tested using the microtetrazolium assay.
Results: The efficacy of IJTEE in eradicating the biofilm was equal to that of chlorhexidine against the early phase of biofilm formation. IJTEE is more
effective against S. sanguinis biofilm formation than against P. gingivalis biofilm formation.
Conclusion: IJTEE can eradicate S. sanguinis and P. gingivalis biofilms.

Keywords: Identified Javanese turmeric ethanol extract, Streptococcus sanguinis, Porphyromonas gingivalis, Biofilm eradication

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How to Cite
YANUAR, R., SUNIARTI, D. F., & DJOHAN, W. (2019). EFFICACY OF JAVANESE TURMERIC ETHANOL EXTRACT IN ERADICATING STREPTOCOCCUS SANGUINIS AND PORPHYROMONAS GINGIVALIS BIOFILM. International Journal of Applied Pharmaceutics, 11(1), 18-22. https://doi.org/10.22159/ijap.2019.v11s1.155
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