A CASE REPORT OF NADROPARIN INDUCED HYPERKALEMIA

  • Balaji O Postgraduate student, Department of Pharmacology, KMC Manipal
  • Bharti Chogtu Associate Professor, Department of pharmacoogy, KMC Manipal
  • Navin Patil Assistant Professor, Department of pharmacology, KMC Manipal, manipal university

Abstract

ABSTRACT
Nadroparin, a low molecular weight heparin, has prophylactic and therapeutic use in thromboembolic disorder. In a patient with carcinoma ovary
stage 3 B, nadroparin was given prophylactically for deep vein thrombosis (DVT) before and after interval cytoreduction surgery. Nadroparin 0.3 ml
was given subcutaneously once daily for 1 day preoperatively and 8 days postoperatively. Rise in serum potassium was observed on the third postoperative
day
suggestive
of hyperkalemia.
Intravenous
fluids were
given,
and the
drug was
stopped
on the 9
post-operative day and hyperkalemia
resolved after 2 days. Monitoring of serum potassium level is essential when Nadroparin is administered prophylactically for more than 7 days for
DVT. As this case illustrates a causal relationship between nadroparin and hyperkalemia, caution must be exercised with nadroparin.
Keywords: Nadroparin, Hyperkalemia, Thrombosis.
th

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How to Cite
O, B., B. Chogtu, and N. Patil. “A CASE REPORT OF NADROPARIN INDUCED HYPERKALEMIA”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 9, no. 7, Aug. 2016, pp. 3-4, https://innovareacademics.in/journals/index.php/ajpcr/article/view/13115.
Section
Case Study(s)

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