• Balaji O Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
  • Amita d Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
  • Navin P Assistant professor, Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.


Anticancer therapy is always known to cause various side effects. L-asparaginase used in the treatment of adult T-cell lymphoblastic leukemia is a
novel class of drug, an enzyme produced from plants as well as microorganisms except human. It is known to cause various adverse reactions including life-threatening neurological complications and thrombotic disorders. Hence, we report a case of hypofibrinogenemia associated with L-asparaginase in a patient treated for T-cell adult lymphoblastic leukemia.


Keywords: L-asparaginase, Hypofibrinogenemia, Adverse effect, Leukemia


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How to Cite
O, B., Amita d, and N. P. “L-ASPARAGINASE INDUCED HYPOFIBRINOGENEMIA: A CASE REPORT”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 5, May 2017, pp. 11-12, doi:10.22159/ajpcr.2017.v10i5.17320.
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