DAPSONE INDUCED DRESS: A CASE REPORT

  • Balaji Ommurugan Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
  • Amita Priya Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
  • Manu Matthew George Post graduate , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.
  • Meena Kuamri Kamalkishore Associate professor, Kasturba Medical college , Manipal university , Manipal.
  • Mohan Babu Vittalrao Amberkar Associate Professor , Department of Pharmacology, Kasturba Medical college , Manipal university , Manipal.

Abstract

Drug reaction with eosinophilia and systemic symptoms. is a very dangerous adverse drug effect causing rashes, eosinophilia, and multiple organ damage. Many drugs are implicated in causing DRESS with most common ones being antimicrobials and antiepileptics. Dapsone used in the treatment of Hansen’s disease as a first-line agent is known for causing many side effects ranging from nausea, vomiting, insomnia, anaphylaxis, hypersensitivity reactions, rashes, muscle weakness, abdominal pain, and so on. Hence, we report a rare case of dapsone-induced DRESS in a tertiary care hospital in South India.

 

Keywords: Dapsone, Adverse effect, Liver toxicity, Rashes, Eosinophilia

References

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Ommurugan, B., A. Priya, M. M. George, M. K. Kamalkishore, and M. B. V. Amberkar. “DAPSONE INDUCED DRESS: A CASE REPORT”. Asian Journal of Pharmaceutical and Clinical Research, Vol. 10, no. 5, May 2017, pp. 4-5, doi:10.22159/ajpcr.2017.v10i5.17554.
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