• Panal Sitorus Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Sumatera Utara, Indonesia.
  • Poppy Anjelisazaitun Hasibuan Department of Pharmacology, Faculty of Pharmacy, University of Sumatera Utara, Indonesia.
  • Denny Satria Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Sumatera Utara, Indonesia.



Phenolic, Flavonoid, Antioxidant, P fel-terrae Lour, Ethanol, Herbs


Objective: To evaluate total phenolic, flavonoid content (TFC and TPC) andantioxidant activity of ethyl acetate fraction (ETF) of Picria fel-terrae Lour. herbs.

Methods: TPC and TFC in ETF were determined by Folin–Ciocalteu and colorimetric methods, and antioxidant activity was determined by 1,1-diphenyl- 2-picrylhydrazyl (DPPH) method.

Results: ETF was found to contain low levels of phenolic (17.71±1.26 mg gallic acid equivalent/g), total flavonoid (14.43±0.03 mg quercetin equivalents/g). Antioxidant activity from DPPH assay was measured as inhibitory concentration 25.72±0.13 μg/mL.

Conclusions: The results reveal that ETF of P. fel-terrae Lour. herbs has strong antioxidant activity. Our further study is to the isolation of compounds which responsible for antioxidant components.


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Author Biography

Panal Sitorus, Department of Pharmaceutical Biology, Faculty of Pharmacy, University of Sumatera Utara, Indonesia.

Department of Pharmaceutical Biology


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How to Cite

Sitorus, P., P. A. Hasibuan, and D. Satria. “TOTAL PHENOLIC AND FLAVONOID CONTENTS AND ANTIOXIDANT ACTIVITY OF ETHANOL FRACTION OF PICRIA FEL-TERRAE (LOUR.) HERBS”. Asian Journal of Pharmaceutical and Clinical Research, vol. 10, no. 7, July 2017, pp. 243-5, doi:10.22159/ajpcr.2017.v10i7.17982.



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