ASSESSMENT OF PHYSICOCHEMICAL PROPERTIES AND PHYTOCHEMICAL CONSTITUENTS ALONG WITH ANTIBACTERIAL POTENTIAL OF TARENNA POLYCARPA LEAF FRACTIONS


Bunga Rimta Barus, Panal Sitorus, Masfria Masfria

Abstract


 Objective: The aim was to investigate the physicochemical analysis, preliminary phytochemical screening and further evaluation of its antibacterial activity from morbesi-besi (Tarenna polycarpa) leaf ethyl acetate and hexane fractions (HF).

Methods: The physicochemical parameters were carried out as per the World Health Organization (WHO) guideline from its ethanolic extract. The phytochemical screening was performed as per Indonesia Pharmacopoeia and conventional method on its ethyl acetate and HF. Ethyl acetate and HF at different concentration were evaluated using agar well diffusion assay.

Result: The plant was found to be free from contaminations. Morbesi-besi leaf fractions are composed of flavonoids, glycosides, saponins, tannins, steroids, and triterpenoids. The phytochemical screening showed only ethyl acetate of lotus leaf extract contains the flavonoids. The antibacterials assay showed that ethyl acetate fraction was better than HF from the inhibition zone.

Conclusion: From the outcomes of this study, morbesi-besi leaf (T. polycarpa) possess potential antibacterial activity.


Keywords


Tarenna polycarpa, Fractions, Antimicrobial, Phytochemical, Physicochemical, Agar well diffusion method.

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About this article

Title

ASSESSMENT OF PHYSICOCHEMICAL PROPERTIES AND PHYTOCHEMICAL CONSTITUENTS ALONG WITH ANTIBACTERIAL POTENTIAL OF TARENNA POLYCARPA LEAF FRACTIONS

Topics

Biological Pharmacy

Keywords

Tarenna polycarpa, Fractions, Antimicrobial, Phytochemical, Physicochemical, Agar well diffusion method.

DOI

10.22159/ajpcr.2018.v11i4.23641

Date

01-04-2018

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Vol 11 Issue 4 April 2018 Page: 78-80

Print ISSN

0974-2441

Online ISSN

2455-3891

Authors & Affiliations

Bunga Rimta Barus
Department of Biological Pharmacy, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.
Indonesia

Panal Sitorus
Department of Biological Pharmacy, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.
Indonesia

Masfria Masfria
Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Sumatera Utara, Medan, Indonesia.
Indonesia


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