HYPOGLYCEMIC ACTIVITY OF ETHANOLIC EXTRACT OF SAURAUIA VULCANI KORTH. LEAVES
Keywords:Hypoglycemic, Saurauia vulcani Korth, Leaves, Extract, Ethanol
Â Objective:Â The aim of this study was to investigate the hypoglycemic activity of ethanol extract ofÂ Saurauia vulcaniÂ Korth. leaves.
Methods:Â S. vulcaniÂ Korth. leaf powder was extracted by maceration method with ethanol 96%. Hypoglycemic activity was examined on rats which is induced with streptozotocin 40 mg/Kg body weight (BW) at dose of 50; 100; and 200 mg/Kg BW.
Results:Â Hypoglycemic activity of the extract in diabetic rats showed a significant reduction in blood glucose levels (p<0.001) at dosage 50 mg/Kg BW.
Conclusion:Â The results reveal that ethanol extract ofÂ S. vulcaniÂ Korth. leaves has hypoglycemic activity. Our further study is to assess mechanism action as antidiabetic.
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