ANTIBACTERIAL ACTIVITY OF FRUIT BANANA STONE AND MECHANISM

Authors

  • Panal Sitorus Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia.
  • Dwi Suryanto, Hepni Department of Pharmaceutical Biology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11s1.26598

Keywords:

Banana stone, Antibacterial, Mechanism

Abstract

Objective: The purpose of this study was to determine the strength of antibacterial activity of the fraction of banana stone and its mechanism.

Methods: The antibacterial activity test was performed using the diffusion method by measuring the diameter of the clear zone around the disc paper.

Results: The results of antibacterial activity test showed that ethyl acetate fraction was more effective against bacterium Staphylococcus aureus, Staphylococcus epidermidis, and Propionibacterium acnes compared to n-hexane fraction.

Conclusion: The resulting cellular metabolite leak showed that cell leakage in the three bacteria due to ethyl acetate fraction had leaked more protein than nucleic acid, while the leakage of more dissolved K+ ion than Ca2 + ions.

References

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Published

2018-04-26

How to Cite

Sitorus, P., and D. S. Hepni. “ANTIBACTERIAL ACTIVITY OF FRUIT BANANA STONE AND MECHANISM”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 13, Apr. 2018, pp. 167-70, doi:10.22159/ajpcr.2018.v11s1.26598.

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