ANALYSIS OF TRENDS OF HYPERTENSIONS RELATING TO THE LEAVES AND CALCULATIONS IN BLOOD IN EMPLOYEE AND RECOVERY: CASE STUDY IN PLACE OF FINAL DISPOSAL (FD) MEDAN - MARELAN.

Authors

  • Muharni Saputri Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia. http://orcid.org/0000-0002-2263-566X
  • Urip Harahap Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia.
  • Muchlisyam Muchlisyam Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia.

DOI:

https://doi.org/10.22159/ajpcr.2018.v11i2.22360

Keywords:

Hypertension, Lead, Calcium, Final disposal

Abstract

 Objective: The aim of this study was to determine the relationship between lead and calcium to hypertension.

Methods: This study uses causal comparative cross-sectional study, which subjects of study as many as 31 people consisting of 10 people in Group I (employees of final disposal [FD]), 17 people in Group II (scavengers who move in FD), and 4 people in Group III (control). Confounding variables in this study are the working period, age, and body mass index. Determining calcium content performed acetylene flame atomic absorption spectrophotometry-air while the lead is done by atomic absorption spectrophotometry graphite furnace method.

Results: The results of the study showed differences of concentration lead of each group. In Group II on day 30 it contained a lead level of 29.9141 μg/DL. This level has exceeded the threshold set by the WHO. Statistical test results using Rank Spearman correlation showed no relationship between lead and calcium to hypertension, the p value of each group was 0.187, 0.819, and 1.00.

Conclusion: The results of this study can be concluded that the lead and calcium does not affect blood pressure on employees and scavengers in the FD Medan-Marelan.

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Author Biography

Muharni Saputri, Department of Pharmacology, Faculty of Pharmacy, Universitas Sumatera Utara, Medan, Indonesia.

I am Muharni Saputri earning a Pharmacy degree in North Sumatera University in 2010. After graduating until now I work at Tjut Nyak Dhien University Medan as Head of Pharmaceutical Laboratory.
In August 2013 I took the Pharmacy Master Program in Pharmacology Pharmacy and completed it in February 2017 at University of Sumatera Utara. I am now a lecturer at Tjut Nyak Dhien University of Medan Pharmacy Study Program and I can be contacted via muharnisaputri16@gmail.com. My research interests in the field of Pharmacology and Chemistry, but not limited to other fields while still in the realm of pharmacy.

References

Debasish B, Debosree G, Aindrila C, Elina M. Curry leaves as alternative medicine in heavy metal induced occupational health hazards. Int J Pharm Pharm Sci 2016;8:8-20.

Poreba P, Antonowicz J, Andrzejak R. The relationship between occupational exposure to lead and local arterial stiffness and left ventricular diastolic function in individuals with arterial hypertension. J Toxicol Appl Pharm 2011;254:342-8.

Ajah KC, Ademiluyi J, Nnaji CC. Spatiality, seasonality and ecological risks of heavy in the vicinity of a degenerate central municipal dump site in Enugu, Nigeria. J Environ Health Sci Eng 2015;13:1-14.

Muamar A. Every day, Garbage in Marelan Final Disposal to 1500 tons in 2015. Newspaper of Tribun Medan.

Palar H. Pollution and Toxicology Heavy Metals. Jakarta: Rineka Copyright; 2008.

Suherni. Lead Poisoning in Indonesia. Global lead Advice and Support Service. Thesis, 2010. Sydney, Australia: Graduate School of the Environment, Macquarie University.

Ulfa SF. Analysis of Lead (Pb) and Cadmium (Cd) Content in Earthworm Atomic Absorption Spectrophotometry (AAS). Thesis, 2010. Medan: University of North Sumatera.

Victery W, Tyroler H, Vospe R, Grant LD. Summary of Discussion Sessions: Symposium on Lead-blood Pressure Relationship. Environ Health Perspect 1988;78:139-55.

Møller L, Kristensen TS. Blood lead as a cardiovascular risk factor. Am J Epidemiol 1992;136:1091-100.

Rustanti I, Mahawati E. The factors related to blood lead levels in the driver of public transports of karang ayu-panggaron in semarang. J Visikes 2011;10:59-68.

Martin D, Glass TA, Bandeen RK, She W, Schwartz BS. Todd air conditioning. Association of blood lead and tibia lead with blood pressure and hypertension in a community sample of older adults. Am J Epidemiol 2006;163:467-78.

Muchlisyam HU, Silalahi J, Alfian Z. Binding ability of corn cobs hemicellulose toward cadmium. Am J Chem 2013;4:86-93.

Haswell SJ. Atomic Absorption Spectrometry. Vol. 202. New York: Elsivier, Amsterdam; 1991. p. 207-8.

Sudjana N. Statistical Methods. 6th ed. Bandung: Publisher Tarsito; 2005. p. 371.

Adnan S. The influence of lead exposure on the health and quality of male workers cement. Ind Med Mag 2001;51:168-74.

Lustberg M, Silbergeld E. Blood lead levels and mortality. Arch Intern Med 2002;162:2443-9.

Brozovich FV, Nicholson CJ, Degen CV, Gao YZ, Aggarwal M, Morgan KG. Mechanism of vascular smooth muscle contraction and the basic for pharmacologic treatment of smooth muscle disorder. Pharmacol Rev 2016;68:476-532.

Coyle P, Kosnett MJ, Hipkins K. Severe lead poisoning in the plastics industry: A report of three cases. Am J Ind Med 2005;47:172-5.

Gupta S, Singh S, Sharma S. Tolerance against heavy metal toxicity in cyanobacteria: Role of antioxidant defense system. Int J Pharm Pharm Sci 2015;7:9-16.

Urso G. Oxidative caimi stress and endothelial dysfunction. Minerva Med 2011;102:59-77.

Published

01-02-2018

How to Cite

Saputri, M., U. Harahap, and M. Muchlisyam. “ANALYSIS OF TRENDS OF HYPERTENSIONS RELATING TO THE LEAVES AND CALCULATIONS IN BLOOD IN EMPLOYEE AND RECOVERY: CASE STUDY IN PLACE OF FINAL DISPOSAL (FD) MEDAN - MARELAN”. Asian Journal of Pharmaceutical and Clinical Research, vol. 11, no. 2, Feb. 2018, pp. 210-4, doi:10.22159/ajpcr.2018.v11i2.22360.

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