ANTIOXIDANT ACTIVITY AND INHIBITION OF LIPOXYGENASE ACTIVITY ETHANOL EXTRACT OF ENDOSPERM ARENGA PINNATA (WURMB) MERR.


BERNA ELYA

Abstract


Objective: The purpose of this study is to determine the antioxidant activity and the potential inhibition of lipoxygenase activity from sugar palm fruit.
Methods: Antioxidant activity was evaluated by the 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP)

methods.Inhibition of lipoxygenase activity was performed in vitro. Sugar palm fruit was macerated with 95% ethanol.

Results: The results showed that sugar palm fruit ethanol extract has antioxidant activity when using DPPH method with EC of 141.3929 µg/mL and the FRAP method with EC 50 50 of 60.2083 µg/mL. Inhibition test of lipoxygenase activity showed inhibitory concentration 50% value of 71.376 µg/mL.

Conclusions: Ethanol extract of endosperm Arenga pinnata has antioxidant activity, as determined using the DPPH method with EC of 141.3929 µg/mL and the FRAP method with EC
50 of 60.2083 µg/mL. 50


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About this article

Title

ANTIOXIDANT ACTIVITY AND INHIBITION OF LIPOXYGENASE ACTIVITY ETHANOL EXTRACT OF ENDOSPERM ARENGA PINNATA (WURMB) MERR.

Date

01-10-2017

Additional Links

Manuscript Submission

Journal

Asian Journal of Pharmaceutical and Clinical Research
Special Issue October 2017 [PTMDS 2017] Page: 76-80

Print ISSN

0974-2441

Online ISSN

2455-3891

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Authors & Affiliations

BERNA ELYA
Department of Pharmacy, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia.
Indonesia


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