PREPARATION OF POWDER FROM BROWN SEAWEED (SARGASSUM PLAGYOPHYLLUM) BY FREEZE-DRYING WITH MALTODEXTRIN AS A STABILIZER

  • Effionora Anwar Department of Pharmaceutical Technology, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia.
  • Hilmia Erianto Department of Pharmaceutical Technology, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia.
  • Kurnia Sari Setio Putri Department of Pharmaceutical Technology, Faculty of Pharmacy, Universitas Indonesia, Depok, 16424, Indonesia.

Abstract

Objective: The aim of this study was to prepare powder from liquid extract with maltodextrin dextrose equivalent 10–15 as a stabilizer using a freezedrying
method to maintain stability during drying process and extend storage time.
Methods: Powders were prepared for four formulas: F1 (without maltodextrin), F2 (2.5% maltodextrin), F3 (5% maltodextrin), and F4 (10%
maltodextrin). Powder from the four formulas was characterized by its phlorotannin concentration, antioxidant activity, water content, morphology,
particle size distribution, pH, and organoleptic activities.
Results: F4 was the best formula because it contained the highest phlorotannin concentration (113.06±1.36) or 0.25%, highest percentage of
inhibition concentration50 (IC50) (4.06% at a concentration of 5000 ppm), and lowest water content (5.16%); moreover, in a stability test, F4 exhibited
a more stable phlorotannin concentration and lower water content than F1, with an optimal storage temperature of 4°C.
Conclusion: Maltodextrin can improve the stability bioactive compounds during the freeze-drying process and storage time.

Keywords: Phlorotannin, Freeze-drying, Sargassum plagyophyllum, Maltodextrin dextrose equivalent 10–15.

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How to Cite
Anwar, E., Erianto, H., & Putri, K. S. S. (2018). PREPARATION OF POWDER FROM BROWN SEAWEED (SARGASSUM PLAGYOPHYLLUM) BY FREEZE-DRYING WITH MALTODEXTRIN AS A STABILIZER. International Journal of Applied Pharmaceutics, 10(1), 348-353. https://doi.org/10.22159/ijap.2018.v10s1.77
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