Skin Care Cream Preparation and Evaluation of Pare (Momordica charantia) Leaves Using Three Difference Base
Skin Care Cream Preparation and Evaluation of Momordica charantia Leaves
Pare or Bitter melon (Momordica charantia L.) fruit from the Cucurbitaceae family has many health benefits but leave of this plant are usually thrown away as waste. While Pare leaves (PL) contained amino acids, vitamin C, vitamin E, flavonoids, phenolic acids and carotenoids that can regenerate skin, affect skin pigmentation and bright dead skin. The purpose of this research is to make a skin care cream that contains bioactive from PL using three kinds of base cream. The dried PL made into powder shape and then extracted using 96% ethanol solvent. The liquid extract was evaporated using a vacuum evaporator until obtained by the viscous extract. PL ethanol extract (PLEE) with concentration 4,00% made into a cosmetic product used vanishing, cold, and hand and body cream as a base. Creams made by mixing the oil phase and water phase at 70oC until cream mass formed then added PLEE at 40oC. All the product creams were evaluated their physical and chemical characteristics and stability tested. Cream of pare leaf ethanol extract had semisolid form, yellowish colour , the peculiar smell of pare ethanol extract, homogeneous, pH 6,37-6,67, easily spread with spreading ability 2081, 21-2835,43 mm2, has viscosity 125000-180000 centipoise and stable 3 months in a room and 60oC temperature storage. Pare leaves can made become a good cream for skin care cosmetic that more benefit and profitable than as a waste. This skin care creams using vanishing base cream, cold cream, and hand and body cream as base creams.
 E. L. Peter et al., “Momordica charantia L. lowers elevated glycaemia in Type 2 Diabetes Mellitus Patients: Systematic review and Meta-analysis,” J. Ethnopharmacol., 2018.
 M. Gupta, S. Sharma, A. K. Gautam, and R. Bhadauria, “Momordica charantia linn . ( Karela ): Nature ’ s silent healer,” no. April 2016, 2011.
 http://www.khasiat.co.id/daun/daun-pare.html, “No Title,” p. 2019, 2019.
 S. Jia, M. Shen, F. Zhang, and J. Xie, “Recent Advances in Momordica charantia?: Functional Components and Biological Activities,” 2017.
 L. Cultivars, J. L. Perez, G. K. Jayaprakasha, and B. S. Patil, Metabolite Profiling and in vitro Biological Activities of Two Commercial Bitter Melon ( Momordica charantia Linn .) Cultivars Vegetable and Fruit Improvement Center , Department of Horticultural Sciences ,. Elsevier Ltd, 2019.
 K. P. S. Kumar and D. Bhowmik, “Traditional medicinal uses and the K. P. S. Kumar and D. Bhowmik, “Traditional medicinal uses and therapeutic benefits of Momordica charantia LINN ",” vol. 4, no. 3, 2016.
 R. J. Ton?i?, S. Kezi?, S. L. Hadžavdi?, and B. Marinovi?, “Skin Barrier and Dry Skin in the Mature Patient,” Clin. Dermatol., 2017.
 J. P. McCook, “Topical Products for the Aging Face,” Clin. Plast. Surg., vol. 43, no. 3, pp. 597–604, 2016.
 A. K. Mohiuddin, “Skin Care Creams?: Formulation and Use,” vol. 2, no. 2, 2019.
 T. Sahu, T. Patel, S. Sahu, B. Gidwani, S. Rawatpura, and C. G. Durg, “Skin Cream as
Topical Drug Delivery System?: A Review,” 2016.
 P. Rai, A. P. Poudyl, and S. Das, “Pharmaceutical Creams and their use in wound healing?: A Review,” vol. 9, pp. 907–912, 2019.
 K. C. Ashara, “Importance of Titurationtechnique on Preparation and Evaluation of Cold Importance of Titurationtechnique on Preparation and Evaluation of Cold Cream,” no. December 2012, pp. 2012–2014, 2016.
 P. Herh, J. Tkachuk, S. Wu, M. Bernzen, and B. Rudolph, “Rheology of pharmaceutical and cosmetic semisolids,” Am. Lab., vol. 30, no. 15, pp. 12–14, 1998.
 H. S. Ali, N. A. Shehab, and E. ahaj B. Mohamed, “Formulation and Evaluation of Herbal Cream From Ziziphus Spina Leaves Extract,” Int. Res. J. Pharm., vol. 4, no. 6, pp. 44–48, 2013.
 D. Shofinita and T. A. G. Langrish, “Spray drying of orange peel extracts: Yield, total phenolic content, and economic evaluation,” J. Food Eng., vol. 139, pp. 31–42, 2014.
 A. M. Jayali, N. H. Soekamto, F. Zenta, N. Zulkifli, and S. Sabir, “Phytochemical Constituent of Methanol Extract in Bark and Leaves from Gofasa Tree ( Vitex cofassus ) Lives in Halmahera , North Maluku which is Potential as Anti-cholesterol,” vol. 11, no. 1, pp. 10–13, 2019.
 M. Agarwal and R. Sarin, “Research Article Titel?: Screening of Antimicrobial Potential of Flavonoids Extracted from Erythrina indica,” vol. 3, no. 1, pp. 22–25, 2014.
 A. P. Reddy, K. Rajitha, B. Sravani, and B. Vanitha, “Formulation and evaluation of Cream From Naturally Containing Plant Extract,” vol. 7, no. 5, pp. 851–862, 2018.
 P. S. Mane, D. J. Kare, A. B. Hogale, S. T. Jadhav, and P. S. Yadav, “Formulation and Evaluation of Polyherbal Vanishing Cream,” vol. 8, no. 5, pp. 953–957, 2019.
 P. I. Of, H. Of, and K. A. S. Pathar, “INTERNATIONAL JOURNAL OF UNIVERSAL,” vol. 3, no. December, pp. 155–176, 2014.
 K. Szewczyk, “Phytochemistry of the genus impatiens ( Balsaminaceae ): A review,” Biochem. Syst. Ecol., vol. 80, no. July, pp. 94–121, 2018.
 A. S. Dhase, S. S. Khadbadi, and S. S. Saboo, “Formulation and Evaluation of Vanishing Herbal Cream of Crude Drugs,” vol. 1, no. 5, pp. 313–318, 2014.
 M. Kwak, H. Ahn, and K. Song, “Rheological investigation of body cream and body lotion in actual application conditions,” vol. 27, no. August, pp. 241–251, 2015.
 F. Veiga, C. Vitorino, A. Figueiras, and A. Sim, “A Tutorial for Developing a Topical Cream Formulation Based on the Quality by Design Approach A Tutorial for Developing a Topical Cream Formulation Based on the Quality by Design Approach,” no. December, 2018.
This work is licensed under a Creative Commons Attribution 4.0 International License.