EFFECTS OF POLYASPARTIC ACID ON REMINERALIZATION OF INTRAFIBRILLAR DENTIN AND SIZE OF HYDROXYAPATITE CRYSTALS

Authors

  • WAVIYATUL AHDI Conservative Dentistry Residency Program, Faculty of Dentistry, Universitas Indonesia, Indonesia.
  • NILAKESUMA DJAUHARIE Department of Conservative Dentistry, Faculty of Dentistry, Universitas Indonesia, Indonesia.
  • RATNA MEIDYAWATI Department of Conservative Dentistry, Faculty of Dentistry, Universitas Indonesia, Indonesia.
  • IKHWAN MUSLIM Conservative Dentistry Residency Program, Faculty of Dentistry, Universitas Indonesia, Indonesia.

DOI:

https://doi.org/10.22159/ijap.2020.v12s2.OP-24

Keywords:

Dentin remineralization, Polyaspartic acid, Non-collagenous protein

Abstract

Objective: The objective of this study was to analyze the intrafibrillar remineralization process and the size of hydroxyapatite crystals formed.
Methods: The samples were divided into four groups. The control group was immersed in a demineralization solution, whereas the remaining three
treatment groups were immersed in a remineralization solution containing polyaspartic acid for 3, 7, or 14 days. The effect of polyaspartic acid on
intrafibrillar remineralization during the polymer-induced liquid-precursor (PILP) process was evaluated using transmission electron microscopy,
and the size of hydroxyapatite crystals was examined through X-ray diffraction.
Results: Significant differences were detected in the intrafibrillar remineralization between the treatment groups (subjected to remineralization for
3, 7, and 14 days) and the demineralized dentin control group. However, no significant differences were detected in the size of hydroxyapatite crystals
between the control and the treatment groups.
Conclusion: Our data suggest that polyaspartic acid enables intrafibrillar remineralization during the PILP process.

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Published

2020-07-24

How to Cite

AHDI, W., DJAUHARIE, N., MEIDYAWATI, R., & MUSLIM, I. (2020). EFFECTS OF POLYASPARTIC ACID ON REMINERALIZATION OF INTRAFIBRILLAR DENTIN AND SIZE OF HYDROXYAPATITE CRYSTALS. International Journal of Applied Pharmaceutics, 12(2), 73-76. https://doi.org/10.22159/ijap.2020.v12s2.OP-24

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