ANTI-CHOLOSETEROL ACTIVITIES OF WHITE (RAPHANUS RAPHANISTRUM) AND RED (RAPHANUS SATIVUS) RADISH ROOTS

  • NOVI YANTIH Faculty of Pharmacy, Pancasila University, Jakarta, 12640, Indonesia
  • WINDA DESTIANA Faculty of Pharmacy, Pancasila University, Jakarta, 12640, Indonesia
  • DIAH KARTIKA PRATAMI Faculty of Pharmacy, Pancasila University, Jakarta, 12640, Indonesia

Abstract

Objective: The purpose of this research is to explore the in vitro activities of white (Raphanus raphanistrum) and red (Raphanus sativus) radish root ethanol extract in decreasing cholesterol levels.


Methods: Ultrasonification method was used in obtaining 96% ethanol extract of white and red radish root. The cholesterol levels were analyzed by visible spectrophotometry, which was validated using Lieberman-Buchard reagents. The decreased cholesterol levels were converted into IC50 values.


Results: The results showed that the IC50 of 96% white and red radish root ethanol extracts were 743.7 and 634.7 µg/ml, respectively. The results of statistical analysis using the T-test obtained a significant value greater than the probability value (P) of 0.05.


Conclusion: Therefore, it was concluded that the activities of 96% ethanol extract of white and red radish roots did not have a significant ability to reduce the in vitro cholesterol levels.

Keywords: Raphanus raphanistrum, Raphanus sativus, Cholesterol, Spectrophotometry

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YANTIH, N., DESTIANA, W., & PRATAMI, D. K. (2021). ANTI-CHOLOSETEROL ACTIVITIES OF WHITE (RAPHANUS RAPHANISTRUM) AND RED (RAPHANUS SATIVUS) RADISH ROOTS. International Journal of Applied Pharmaceutics, 13(2), 24-29. https://doi.org/10.22159/ijap.2021.v13s2.05
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