A REVIEW ON HELICOBACTER PYLORI: ITS BIOLOGY, COMPLICATIONS AND MANAGEMENT


Ashwini P, Sumana Mn, Shilpa U, Mamatha P, Manasa P, Dhananjaya Bl, Farhan Zameer, Nagendra Prasad Mn

Abstract


Helicobacter pylori (HP) emergences in gastro intestinal tracts of human beings are one of the major health concerns in recent times. The infection in the later stages can lead to peptic ulcers and gastric cancers. HP is second commonly encountered pathogen in humans next only to Streptococcus. The virulence of the pathogen is further strengthened by its capability in forming biofilms. There are various therapies to treat this infection which are classified as first line, second line and third line, but are not free from the serious antibiotic resistances which normally are encountered in treating bacterial diseases. Vowing to above reason, it is necessary to search for alternative management strategies with lesser side effects and complications like plant based drugs and designer nutraceutical products which includes herbal extracts, probiotics, phytomedicines, antioxidants, essential oils, flavonoids so-on. In the present study, we have reviewed on the thorough understanding on biology, complications and management of H. Pylori and its infections.

 


Keywords


Peptic ulcers, H. Pylori, Biofilms, Cag A, Vac A, Phytomedicines

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About this article

Title

A REVIEW ON HELICOBACTER PYLORI: ITS BIOLOGY, COMPLICATIONS AND MANAGEMENT

Keywords

Peptic ulcers, H. Pylori, Biofilms, Cag A, Vac A, Phytomedicines

Date

02-05-2015

Additional Links

Manuscript Submission

Journal

International Journal of Pharmacy and Pharmaceutical Sciences
Vol 7, Suppl 1, 2015 (Special Issue: Drugs from Nature) Page: 14-20

Online ISSN

0975-1491

Statistics

248 Views | 748 Downloads

Authors & Affiliations

Ashwini P
JSS University
India

Sumana Mn
JSS Medical College and Hospital, JSS University, JSS Technical Institution Campus, Manasagangothri, Mysore 570006, Karnataka, India
India

Shilpa U
JSS University
India

Mamatha P
JSS University
India

Manasa P
JSS University
India

Dhananjaya Bl
JSS University
India

Farhan Zameer
JSS University
India

Nagendra Prasad Mn
JSS University
India


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